第一集该文比力干,是从欧美国度上下倒置的一则介绍添加剂危害性的该文。若是您对护肤品平安可靠很在乎,或者是现职成份党,建议立即收藏保留,分享给你的亲友老友,让更多的人起头存眷护肤品平安可靠常识,远离化工危害性。
什么是添加剂?
添加剂用于护肤品中,以制止有害细菌和霉菌的繁衍。
常见于:香水、口红、化装品、洗面奶、调养品、面霜、面部和淋浴清洁剂、指甲油、指甲胶、发胶、头发柔顺商品、婴儿化装品、洗澡露/肥皂、彩妆和抗衰老商品。
标签上的留意事项:二氧化硫、DMDM 乙内酰脲、季铵盐 15、二甲基烷基脲、四氟肼基脲、聚二氧化硫脲、羟羟基甘氨酸钠、2-溴-2-硝基丙烷-1,3-环氧化物(溴醇)和乙二醛。对羟基酯甲酸 对羟基酯丁基、对羟基酯丙酮、对羟基酯酸二钠、对羟基酯异丁基、对羟基酯异酸二钠、其它以-对羟基酯酯结尾的成份。苄化物、酯和苄酯。羟基异苯并呋喃啉酮 (MIT):2-methyl-4-isothiazoline-3-one、Neolone 950 添加剂、MI、OriStar MIT 和 Microcare MT。羟基氯异苯并呋喃啉酮 (CIT):5-Chloro-2-methyl-4-isothiazolin-3-one 和 MCI。腈的尿素、2-腈的尿素、Euxyl K® 400(腈的尿素和 1,2-二溴-2,4-二氰基丁烷的氧化物)、PhE。三氯生 (TSC) 和三氯卡班 (TCC)。此外,查抄和苯尿素、苯扎含氟、葡萄糖、环氧硝酸、精油、葡萄柚籽提取物、乳酸、乙酰丙酸、苯甲酸钠钾、环氧硝酸钠、焦氢氧化钠、磺、苯甲酸钠、维生素 E、吡啶硫酮锌。
身心安康问题:肺癌、心血管紊乱、发育副感化、不育副感化、按捺和良多其它身心安康问题。
对羟基酯酯:科学研究申明,在足够的浓度下,对羟基酯酯能够增加人乳癌 MCF-7 细胞核的细胞核增殖,那一般来说被用于激素活性的懦弱量度。[4][5][6]对羟基酯酯是潜在性的心血管障碍物,即便它们可以演示激素。[7]在细胞核科学研究中,已辨认出对羟基酯酯与激素受体的连系较弱。[8]对羟基酯酸二钠也是一类不育毒素,即便它会负面影响女性不育器官并降低精子生成和睾酮程度。[9],[10],[11]详细而言,对羟基酯丁基似乎会毁坏女性不育器官并负面影响不育器官。[12],[13]对小我护肤用品中的对羟基酯丙酮和其它对羟基酯酯会引致紫外线诱导的眼部细胞核损伤和细胞核增殖(细胞核幼生)的毁坏。[14],[15]在对羟基酯酯类中,对羟基酯丙酮一般来说不太受存眷,即便它的激素较少。对羟基酯甲酸被 TEDX Endocrine Disruption Exchange 列入潜在性的心血管障碍物。[16],[17]
二氧化硫:二氧化硫被国度毒理学方案[19]和国际肺癌科学研究机构列入已知的人类致癌物。[20]
释放出来二氧化硫的添加剂:那些添加剂会跟着时间的推移释放出来少量二氧化硫。
DMDM 乙内酰脲是一类释放出来二氧化硫的添加剂 (FRP),用于制止微生物在水性商品中繁衍。它能够在良多对小我护肤用品中找到。[21]
在所有释放出来二氧化硫的添加剂中,四氟肼脲释放出来的二氧化硫最多。[22]
二甲基啉脲是对小我护肤用品中最常用的杀菌剂之一,一般来说与对羟基酯酯连系利用。[23]
聚季铵盐-15是那些 FRP 中最懦弱的,存在于眼影、睫毛膏、调养品和化装品中。[24]几项科学研究申明,大约 22.3% 的消费者对 聚季铵盐-15 过敏。[25]
溴硝丙环氧化物 (2-Bromo-2-Nitropropane)是一类释放出来二氧化硫的添加剂。它被列入潜在性的心血管障碍物。[26]它对水生生物也有剧毒,可引发眼部按捺和呼吸系统按捺。[27],[28]
异苯并呋喃啉酮:科学研究申明,异苯并呋喃啉酮在良多欧洲国度引发过敏性护肤品皮炎[29]。[30]
羟基异苯并呋喃啉酮 (MIT)是护肤品中最次要的碰触性过敏原之一。[31]MIT 还与器官系统副感化[32] 和神经副感化有关。[33]
羟基氯异苯并呋喃啉酮 (CMIT/MCI)在几项临床科学研究中,科学研究人员辨认出眼部按捺最常发作在所含 CMIT 和 MIT/CIT 氧化物的商品中,但在仅所含 MIT 的商品中其实不常见。[34],[35]
以下添加剂越来越多地用于对小我护肤用品。很少有科学研究查抄和那些化合物在对小我护肤用品中利用的程度对身心安康的负面影响。
酯苄酯:几项科学研究辨认出,酯苄酯在培育的人类乳癌细胞核系中表示出激素反响,那申明某种物量具有演示激素的才能。[36]酯苄酯是一类眼部和双眼按捺物,可能会严峻按捺、灼伤和刺痛不育器和头皮。[37]
苯尿素:用于添加剂、溶剂和部分麻醒剂,据报导会在某些业余情况中引发碰触性皮炎,也称为皮炎或带有红色、凸起、发痒肿块的皮疹。[38]它可能对眼部有按捺性,排出高浓度可能会引致中枢神经系统负面影响,并可能在频频或持久碰触时引发眼部过敏。[39]
苯扎含氟:苯扎含氟与业余性哮喘有关。[40]短期碰触对双眼、眼部和呼吸系统有侵蚀性。[41]
葡萄糖:短期碰触葡萄糖会按捺双眼、眼部和呼吸系统。持久(一般来说是业余)碰触可能会引致牙齿侵蚀。[42]它在豚鼠的急性排出科学研究中引发咳嗽,[43]共济失调和小鼠呼吸按捺。[44]
环氧硝酸:环氧硝酸可引致山公癫痫爆发[45] 和大鼠多器官严峻出血。[46]
精油:精油可能所含天然成份,如胡薄荷酮或羟基丁香酚等可能致癌并改动心血管功用的成份。[47]、[48]、[49]
羟基丁香酚(丁香基羟基醚)能够负面影响多个心血管系统[50] 并被 NTP、[51] IARC [52] 和加利福尼亚州 65 号提案列入可能的人类致癌物。[53]
葡萄柚籽提取物 (GSE):葡萄籽提取物自己的存眷度较低,但也可能是一类无效的添加剂。已经辨认出,有时 GSE 与其它添加剂一路保留,[54]那会引致其成效和身心安康问题:苄索含氟、[55]、[56]、[57] 对羟基酯丙酮(见对羟基酯酯)和三氯生(见下文) )。
乳酸:乳酸会按捺眼部和呼吸系统,吞咽时会侵蚀双眼和消化道。[58] , [59]
乙酰丙酸:已知对眼部和双眼有中等按捺性,摄入后有害。[60]
腈的尿素:眼部碰触腈的尿素与过敏反响有关,从湿疹和皮炎[61] 到过敏反响。[62] 已经在口服腈的尿素的婴儿中察看到了急性神经系统负面影响。[63]
苯甲酸钠钾:苯甲酸钠钾可能会引致双眼按捺[64]和碰触性皮炎。[65]
环氧硝酸钠 (DHA-S):在几项大鼠科学研究中,DHA-S 引致多个器官出血和凝血因子耽误。[66]
焦氢氧化钠 (SMB):科学研究辨认出排出 SMB 的原因可能会加剧哮喘症状。[67] SMB 也被辨认出在业余情况中引发皮炎[68]。[69]
苯甲酸钠:苯甲酸钠与眼部按捺、碰触性皮炎(也称为皮炎)或带有红色、凸起、发痒肿块的皮疹以及眼部发红(红斑)、异常积液(水肿)有关,和眼部炎症。[70]
三氯卡班:三氯卡班是一类潜在性的心血管障碍物。[71]科学研究辨认出,在对小我护肤用品中碰触三氯卡班可能会放大内源性激素的感化并加强睾酮。[72]它也是眼部、双眼和呼吸系统的按捺物。[73]
三氯生 (TSC):有证据申明,三氯生是一类心血管障碍物[74]、[75],会负面影响甲状腺功用。[76],[77]多项科学研究申明,三氯生会促进匹敌生素药物和抗菌商品具有抗性的细菌。[78],[79] 证据还申明,三氯生会在生物体内蓄积并危害性情况。[80],[81]
维生素 E(生育酚):几项或多项动物科学研究申明,高剂量会构成肿瘤。[82],[83]饮食弥补维生素 E 已被证明会显着增加身心安康女性患前列腺癌的风险。[84]
吡啶硫酮锌 (Zpt):科学研究辨认出,Zpt 会引致鱼幼虫呈现明显的发育畸形。[85]
其它添加剂:虽然缺乏有关其身心安康负面影响的数据,但仍有几种其它添加剂可用于对小我护肤用品:茴香酸、水杨酸、氯苯那敏、硬脂酮氯化物、磺(阿司匹林)、二葡萄糖酸氯己定、聚氨基丙基双胍和印楝油.
存眷群体:妊妇、婴儿/幼儿和美发/美甲沙龙工做人员。
律例:日本和瑞典制止在护肤品和盥洗用品中利用二氧化硫;[86]在欧盟,对小我护肤用品遭到限造,而且要求在所含那些化学物量的商品上贴上标签;[87]加拿大的集中限造。[88]丹麦制止在儿童长达数年的护肤品中利用某些形式的对羟基酯酯(对羟基酯酸二钠和丁基,它们的异构体和盐)。[89]FDA 没有适用于护肤品添加剂的特殊规定。[90]
欧盟规定了护肤品中允许利用的各类添加剂的品种和数量。它是最全面的护肤品/对小我护理监管指南之一,为世界各地的良多监管机构设定了尺度。清单上包罗添加剂,例如:三氯生、三氯卡班、腈的尿素、酯苄酯、羟基异苯并呋喃啉酮、吡啶硫酮锌、苯扎含氟、苯尿素和一些精油。
若何制止:阅读标签,制止利用所含大大都对羟基酯酯和所有释放出来二氧化硫的添加剂的商品。若是您对其它成份懦弱,也应制止利用那些成份。
若是您想领会更多添加剂平安可靠问题或者有其它疑惑,请私信联络我。
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